HORDB

ID: hor004293
Uniprot ID: F5XVF6
Protein name: Ci-TK-II
Gene name: NA
Organism: Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)
Family: Tachykinin family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Ciona (genus), Cionidae (family), Phlebobranchia (order), Ascidiacea (class), Tunicata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: NA
GO CC: NA

Sequence: NLLSLLQHAIETANNAYRSPR
Length: 21(96-116)
Propeptide: MKINVPAFFKLALFVLMLDKLNVSATPLLQRMADQNDWPAVYANLPRRVFASNDLRIQETEDNSMSKDFEDFISRLTQQATRNRRSAPQCDKVKRNLLSLLQHAIETANNAYRSPRKRHAPMRIVSRSWGSFCQYVHDRLKSTYCLVHNHPWLFRESTDGILGTIDTMILLLQQDMNIIASSDSTFSYNHFDKSRLTCPLSNLSDREAESLVKEELFSVADLLRRACL
Signal peptide: MKINVPAFFKLALFVLMLDKLNVSA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Function: NA
Mechanism: The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry.
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor004293_AF2.pdb

hor004293_ESM.pdb

Mass:	273860	Formula:	C103H169N33O32
Absent amino acids:	CDFGKMVW	Common amino acids:	L
pI:	9.35	Basic residues:	3
Polar residues:	7	Hydrophobic residues:	8
Hydrophobicity:	-46.67	Boman Index:	-4625
Half-Life:	1.4 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	107.14
Instability Index:	7617.62	Extinction Coefficient cystines:	1490
Absorbance 280nm:	74.5

PubMed ID: 21467196
Title: Peptidomic Analysis of the Central Nervous System of the Protochordate, Ciona Intestinalis: Homologs and Prototypes of Vertebrate Peptides and Novel Peptides