General Information

  • ID:  hor004293
  • Uniprot ID:  F5XVF6
  • Protein name:  Ci-TK-II
  • Gene name:  NA
  • Organism:  Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)
  • Family:  Tachykinin family
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Ciona (genus), Cionidae (family), Phlebobranchia (order), Ascidiacea (class), Tunicata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  NLLSLLQHAIETANNAYRSPR
  • Length:  21(96-116)
  • Propeptide:  MKINVPAFFKLALFVLMLDKLNVSATPLLQRMADQNDWPAVYANLPRRVFASNDLRIQETEDNSMSKDFEDFISRLTQQATRNRRSAPQCDKVKRNLLSLLQHAIETANNAYRSPRKRHAPMRIVSRSWGSFCQYVHDRLKSTYCLVHNHPWLFRESTDGILGTIDTMILLLQQDMNIIASSDSTFSYNHFDKSRLTCPLSNLSDREAESLVKEELFSVADLLRRACL
  • Signal peptide:  MKINVPAFFKLALFVLMLDKLNVSA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry.
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:   NA
  • IC50:  NA
  • EC50:  NA
  • ED50:  NA
  • Kd:  NA
  • Half life:  NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-F5XVF6-F1(AlphaFold_DB_ID)

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor004293_AF2.pdbhor004293_ESM.pdb

Physical Information

Mass: 273860 Formula: C103H169N33O32
Absent amino acids: CDFGKMVW Common amino acids: L
pI: 9.35 Basic residues: 3
Polar residues: 7 Hydrophobic residues: 8
Hydrophobicity: -46.67 Boman Index: -4625
Half-Life / Aliphatic Index: 1.4 hour Aliphatic Index: 107.14
Instability Index: 7617.62 Extinction Coefficient cystines: 1490
Absorbance 280nm: 74.5

Literature

  • PubMed ID:  21467196
  • Title:  Peptidomic Analysis of the Central Nervous System of the Protochordate, Ciona Intestinalis: Homologs and Prototypes of Vertebrate Peptides and Novel Peptides